FDA Drug Recalls

Recalls / Class II

Class IID-0081-2024

Product

Gynazole-1, (Butoconazole Nitrate) Vaginal Cream USP, 2%, Net Wt 5.8 g per pre-filled applicator, packaged in 1 prefilled applicator per carton, Rx Only, Manufactured By Padagis, Yeruham, Israel; Distributed By: Padagis, Allegan, MI 49010. NDC: 45802-396-01

Brand name
Gynazole 1
Generic name
Butoconazole Nitrate
Active ingredient
Butoconazole Nitrate
Route
Vaginal
NDC
45802-396
FDA application
ANDA200923
Affected lot / code info
Lot#: 164185, Exp. Date 4/2024

Why it was recalled

Incorrect Product Formulation: Hydrophilic Colloidal Silica was used to manufacture the product rather than Hydrophobic Colloidal Silica as required by the manufacturing process.

Recalling firm

Firm
Padagis US LLC
Manufacturer
Padagis Israel Pharmaceuticals Ltd
Notification channel
Letter
Type
Voluntary: Firm initiated
Address
3940 Quebec Ave N, N/A, Minneapolis, Minnesota 55427-1244

Distribution

Quantity
10,512 cartons
Distribution pattern
Nationwide within the United States

Timeline

Recall initiated
2023-09-28
FDA classified
2023-10-31
Posted by FDA
2023-11-08
Status
Ongoing

Source: openFDA Drug Enforcement endpoint. Recall record D-0081-2024. The FDA issues recall classifications as health-hazard assessments, not legal findings; for legal claims consult a licensed attorney.