FDA Drug Recalls

Recalls / Class I

Class ID-0210-2025

Class I— FDA's most serious classification, issued when there is a reasonable probability that use of or exposure to the drug will cause serious adverse health consequences or death.

Product

Astagraf XL (tacrolimus extended-release capsules) 0.5 mg, 30-count bottles, RX Only, Product of Japan, Distributed by: Astellas Pharma US Inc., Northbrook, IL 60062, NDC 0469-0647-73.

Brand name
Astagraf Xl
Generic name
Tacrolimus Extended-release Capsules
Active ingredient
Tacrolimus
Route
Oral
NDCs
0469-0647, 0469-0677, 0469-0687
FDA application
NDA204096
Affected lot / code info
Lot# 0R3092A, EXP 03/31/2026

Why it was recalled

Failed Tablet/Capsule Specifications: Bottles shipped to the USA may contain empty capsules

Recalling firm

Firm
Astellas Pharma US Inc.
Manufacturer
Astellas Pharma US, Inc.
Notification channel
Press Release
Type
Voluntary: Firm initiated
Address
2375 Waterview Dr, Northbrook, Illinois 60062-6145

Distribution

Quantity
3,500 30-count bottles
Distribution pattern
Nationwide in the USA

Timeline

Recall initiated
2024-12-23
FDA classified
2025-01-29
Posted by FDA
2025-02-05
Status
Ongoing

Source: openFDA Drug Enforcement endpoint. Recall record D-0210-2025. The FDA issues recall classifications as health-hazard assessments, not legal findings; for legal claims consult a licensed attorney.

Class I recall: Astagraf Xl · FDA Drug Recalls