FDA Drug Recalls

Recalls / Class III

Class IIID-0286-2019

Product

AMITIZA (lubiprostone) capsules 8 mcg. 60-count bottle, Rx Only. Marketed by: Sucampo Pharma Americas, LLC, Rockville MD 20850 and Takeda Pharmaceuticals America, Inc. Deerfield, IL 60015. Active Ingredient made in Japan, encapsulated in the United States. NDC 64764-080-60

Brand name
Amitiza
Generic name
Lubiprostone
Active ingredient
Lubiprostone
Route
Oral
NDCs
64764-080, 64764-240
FDA application
NDA021908
Affected lot / code info
Lot # 3098628-61, exp. date 02/28/2021

Why it was recalled

Failed Impurities/Degradation Specifications:Elevated levels of a known impurity in the 20-month stability sample testing.

Recalling firm

Firm
Takeda Development Center Americas, Inc.
Manufacturer
Takeda Pharmaceuticals America, Inc.
Notification channel
Letter
Type
Voluntary: Firm initiated
Address
1 Takeda Pkwy, 4034BB1, Deerfield, Illinois 60015-5713

Distribution

Quantity
69,075 60-count bottles (4,144,500 capsules)
Distribution pattern
Product was distributed to 32 distributors throughout the United States.

Timeline

Recall initiated
2018-11-06
FDA classified
2018-11-28
Posted by FDA
2018-11-21
Terminated
2019-06-20
Status
Terminated

Source: openFDA Drug Enforcement endpoint. Recall record D-0286-2019. The FDA issues recall classifications as health-hazard assessments, not legal findings; for legal claims consult a licensed attorney.

Class III recall: Amitiza · FDA Drug Recalls