FDA Drug Recalls

Recalls / Class II

Class IID-0286-2025

Product

Neupogen (filgrastim) For Injection, 480 mcg/1.6 mL (300 mcg/1 mL), 1.6 mL single Dose Vial, Rx Only, For Subcutaneous or Intravenous Use Only, Sterile Solution - No Preservative, Amgen Inc. Thousand Oaks, CA 91320, NDC 55513-546-01 (vial), NDC 55513-546-10 (box).

Brand name
Neupogen
Generic name
Filgrastim
Active ingredient
Filgrastim
Route
Intravenous, Subcutaneous
NDCs
55513-209, 55513-530, 55513-546, 55513-924
FDA application
BLA103353
Affected lot / code info
Lot 1147308, 1154183, Exp.: 2/28/2025; 1156807, 1160222, Exp.: 6/30/2025; 1160223, 1163912, 1167352, Exp.: 2/28/2026; 1171365, 1175057, 1176250, Exp.: 11/30/2026.

Why it was recalled

Stability data does not support expiry: the products have the potential to be out of specification at the time of expiry of 36-months.

Recalling firm

Firm
Amgen, Inc.
Manufacturer
Amgen, Inc
Notification channel
Letter
Type
Voluntary: Firm initiated
Address
1 Amgen Center Dr, N/A, Thousand Oaks, California 91320-1730

Distribution

Quantity
258,750 Vials
Distribution pattern
Nationwide in the U.S.A. and Belgium/Luxembourg, Brazil, Chile, Colombia, France/French Guiana, Germany, Ireland, Italy/San Marino, Netherlands, Poland, Spain/Andorra, Sweden, Finland, Switzerland/Liechtenstein, United Kingdom of Great Britain and Northern Ireland, Ireland, Denmark, Canada, Hong Kong, Philippines, Israel, Malaysia, Saudi Arabia, Gibraltar.

Timeline

Recall initiated
2025-02-27
FDA classified
2025-03-18
Posted by FDA
2025-03-26
Status
Ongoing

Source: openFDA Drug Enforcement endpoint. Recall record D-0286-2025. The FDA issues recall classifications as health-hazard assessments, not legal findings; for legal claims consult a licensed attorney.

Class II recall: Neupogen · FDA Drug Recalls