FDA Drug Recalls

Recalls / Class II

Class IID-0336-2021

Product

Minivelle (estradiol transdermal system) Delivers 0.075 mg/day, 8 patches/box, Rx only, Mfd. by: Noven Pharmaceuticals, Inc. Miami, Florida 33186 Dist. by: Noven Therapeutics, LLC Miami, Florida 33186, NDC 68968-6675-8

Brand name
Minivelle
Generic name
Estradiol
Active ingredient
Estradiol
Route
Transdermal
NDCs
68968-6610, 68968-6625, 68968-6637, 68968-6650, 68968-6675
FDA application
NDA203752
Affected lot / code info
Lot #: 88584 Exp. 03/2022

Why it was recalled

Defective Delivery System: Out of specification for release rate testing and shear, an attribute related to the adhesive properties of the transdermal patches. As a result, patients could experience patches that do not stick well to the skin.

Recalling firm

Firm
Noven Pharmaceuticals Inc
Manufacturer
Noven Therapeutics, LLC
Notification channel
Letter
Type
Voluntary: Firm initiated
Address
11960 Sw 144th St, N/A, Miami, Florida 33186-6109

Distribution

Quantity
12060 cartons
Distribution pattern
Nationwide within the United States

Timeline

Recall initiated
2021-04-16
FDA classified
2021-04-20
Posted by FDA
2021-04-28
Terminated
2024-10-11
Status
Terminated

Source: openFDA Drug Enforcement endpoint. Recall record D-0336-2021. The FDA issues recall classifications as health-hazard assessments, not legal findings; for legal claims consult a licensed attorney.

Class II recall: Minivelle · FDA Drug Recalls