FDA Drug Recalls

Recalls / Class II

Class IID-0337-2021

Product

Estradiol Transdermal System Delivers 0.0375 mg/day, 8 Systems/box, Rx only, Mfd. by: Noven Pharmaceuticals, Inc. Miami, Florida 33186 Dist. by: Noven Therapeutics, LLC Miami, Florida 33186, NDC 68968-3437-8

Brand name
Estradiol
Generic name
Estradiol
Active ingredient
Estradiol
Route
Transdermal
NDCs
68968-3410, 68968-3425, 68968-3437, 68968-3450, 68968-3475
FDA application
NDA203752
Affected lot / code info
Lot #: 88321 Exp. 02/2022

Why it was recalled

Defective Delivery System: Out of specification for release rate testing and shear, an attribute related to the adhesive properties of the transdermal patches. As a result, patients could experience patches that do not stick well to the skin.

Recalling firm

Firm
Noven Pharmaceuticals Inc
Manufacturer
Noven Therapeutics, LLC
Notification channel
Letter
Type
Voluntary: Firm initiated
Address
11960 Sw 144th St, N/A, Miami, Florida 33186-6109

Distribution

Quantity
10872 cartons
Distribution pattern
Nationwide within the United States

Timeline

Recall initiated
2021-04-16
FDA classified
2021-04-20
Posted by FDA
2021-04-28
Terminated
2024-10-11
Status
Terminated

Source: openFDA Drug Enforcement endpoint. Recall record D-0337-2021. The FDA issues recall classifications as health-hazard assessments, not legal findings; for legal claims consult a licensed attorney.