FDA Drug Recalls

Recalls / Class I

Class ID-0488-2025

Class I— FDA's most serious classification, issued when there is a reasonable probability that use of or exposure to the drug will cause serious adverse health consequences or death.

Product

Sulfamethoxazole and Trimethoprim Tablets, USP, 400 mg/80 mg, Rx Only, a) 100 Tablets per Bottle, NDC: 65162-271-10, b) 500 Tablets per Bottle, NDC: 65162-271-50, Manufactured by: Amneal Pharmaceuticals Pvt. Ltd., Oral Solid Dosage Unit, Ahmedabad, 382213, INDIA, Distributed by: Amneal Pharmaceuticals LLC, Bridgewater, NJ 08807.

Brand name
Sulfamethoxazole And Trimethoprim
Generic name
Sulfamethoxazole And Trimethoprim
Active ingredients
Sulfamethoxazole, Trimethoprim
Route
Oral
NDCs
65162-271, 65162-272
FDA application
ANDA076899
Affected lot / code info
Lot #s: a) AM241019, AM241020, Exp. 06/30/2027 b) AM241019A, Exp 06/30/2027

Why it was recalled

Microbial contamination of non-sterile products: tablets may exhibit black spots due to microbial contamination.

Recalling firm

Firm
Amneal Pharmaceuticals, LLC
Manufacturer
Amneal Pharmaceuticals LLC
Notification channel
Press Release
Type
Voluntary: Firm initiated
Address
400 Crossing Blvd Fl 3, Bridgewater, New Jersey 08807-2863

Distribution

Quantity
6396 bottles
Distribution pattern
Nationwide in the USA

Timeline

Recall initiated
2025-06-02
FDA classified
2025-06-23
Posted by FDA
2025-06-18
Status
Ongoing

Source: openFDA Drug Enforcement endpoint. Recall record D-0488-2025. The FDA issues recall classifications as health-hazard assessments, not legal findings; for legal claims consult a licensed attorney.