FDA Drug Recalls

Recalls / Class II

Class IID-0553-2021

Product

Methotrexate Injection, USP 50 mg/2mL (25 mg/mL) 5 x 2mL Single-Dose Vials, Sterile, Rx Only, Distributed by Hospira, Inc. Lake Forest, IL 60045. NDC 61703-350-38.

Brand name
Methotrexate
Generic name
Methotrexate
Active ingredient
Methotrexate Sodium
Route
Intramuscular, Intravenous, Subcutaneous
NDCs
61703-350, 61703-408
FDA application
NDA011719
Affected lot / code info
H074437AA

Why it was recalled

CGMP Deviations: Intermittent exposure to temperature excursion during storage.

Recalling firm

Firm
Cardinal Health Inc.
Manufacturer
Hospira, Inc.
Notification channel
Letter
Type
Voluntary: Firm initiated
Address
7000 Cardinal Pl, N/A, Dublin, Ohio 43017-1091

Distribution

Quantity
341 vials
Distribution pattern
FL, GA, SC

Timeline

Recall initiated
2021-03-15
FDA classified
2021-05-24
Posted by FDA
2021-06-02
Terminated
2024-06-17
Status
Terminated

Source: openFDA Drug Enforcement endpoint. Recall record D-0553-2021. The FDA issues recall classifications as health-hazard assessments, not legal findings; for legal claims consult a licensed attorney.

Class II recall: Methotrexate · FDA Drug Recalls