FDA Drug Recalls

Recalls / Class II

Class IID-0594-2025

Product

Carvedilol Tablets USP, 12.5 mg, 100- Tablets, (10x10) cartons, Rx Only, Packaged and distributed by Major Pharmaceuticals, Indianapolis, IN, 46268, USA, NDC 0904-7307-61

Brand name
Carvedilol
Generic name
Carvedilol
Active ingredient
Carvedilol
Route
Oral
NDCs
0904-7305, 0904-7306, 0904-7307, 0904-7308
FDA application
ANDA078251
Affected lot / code info
Lot #: T05693, Exp. Date 03/2026

Why it was recalled

CGMP Deviations: Results for N-Nitroso Carvedilol Impurity-1 (NNCI) impurity observed to be above the FDA-recommended limit of NMT 4.0 ppm

Recalling firm

Firm
The Harvard Drug Group LLC dba Major Pharmaceuticals and Rugby Laboratories
Manufacturer
Major Pharmaceuticals
Notification channel
Letter
Type
Voluntary: Firm initiated
Address
341 Mason Rd, N/A, La Vergne, Tennessee 37086-3606

Distribution

Quantity
26,628 cartons
Distribution pattern
Product was distributed nationwide within the United States.

Timeline

Recall initiated
2025-08-20
FDA classified
2025-08-21
Posted by FDA
2025-08-27
Status
Ongoing

Source: openFDA Drug Enforcement endpoint. Recall record D-0594-2025. The FDA issues recall classifications as health-hazard assessments, not legal findings; for legal claims consult a licensed attorney.

Class II recall: Carvedilol · FDA Drug Recalls