FDA Drug Recalls

Recalls / Class II

Class IID-0676-2025

Product

Brimonidine Tartrate/Timolol Maleate Ophthalmic Solution, 0.2%/0.5%, a) 5 mL and b) 10 mL, Rx Only, Sterile, Manufactured by: Apotex Inc., Richmond Hill, Ontario, Canada, L4C 5H2, Manufactured for: Apotex Corp., Weston, FL 33326, NDC 60505-0589-1 (5 mL), NDC 60505-0589-2 (10 mL).

Brand name
Brimonidine Tartrate/timolol Maleate Ophthalmic Solution
Generic name
Brimonidine Tartrate And Timolol Maleate
Active ingredients
Brimonidine Tartrate, Timolol Maleate
Route
Ophthalmic
NDC
60505-0589
FDA application
ANDA091442
Affected lot / code info
a) lot # VE0614 exp. date 12/2025 UPC:(01)00360505058914 (5 mL) b) lot # VE0616 exp. date 12/2025 UPC:(01)0(03)60505058921 (10 mL)

Why it was recalled

Lack of Assurance of Sterility; atypical weight loss due to improper bottle sealing leading to potential sterility concerns

Recalling firm

Firm
Apotex Corp.
Notification channel
Letter
Type
Voluntary: Firm initiated
Address
2400 N Commerce Pkwy Ste 400, N/A, Weston, Florida 33326-3253

Distribution

Quantity
151,034 bottles
Distribution pattern
Nationwide in the US

Timeline

Recall initiated
2025-09-05
FDA classified
2025-09-30
Posted by FDA
2025-10-08
Status
Ongoing

Source: openFDA Drug Enforcement endpoint. Recall record D-0676-2025. The FDA issues recall classifications as health-hazard assessments, not legal findings; for legal claims consult a licensed attorney.