FDA Drug Recalls

Recalls / Class I

Class ID-1049-2014

Class I— FDA's most serious classification, issued when there is a reasonable probability that use of or exposure to the drug will cause serious adverse health consequences or death.

Product

Soliris (eculizumab) Concentrated Solution for Intravenous Infusion Only, 300 mg/30 mL (10 mg/mL), 30 mL Single-Use Vial, Rx only, Manufactured by: Alexion Pharmaceuticals, Inc., Cheshire, CT 06410, NDC 25682-001-01, UPC 3 25682-001-01 6.

Brand name
Soliris
Generic name
Eculizumab
Active ingredient
Eculizumab
Route
Intravenous
NDC
25682-001
FDA application
BLA125166
Affected lot / code info
Lot #: 10001-1, Exp 07/14; 10010A, Exp 10/15

Why it was recalled

Presence of Particulate Matter: Failed the appearance test for the presence of visible particles.

Recalling firm

Firm
Alexion Pharmaceuticals, Inc.
Manufacturer
Alexion Pharmaceuticals Inc.
Notification channel
E-Mail
Type
Voluntary: Firm initiated
Address
352 Knotter Dr, Cheshire, Connecticut 06410-1138

Distribution

Quantity
21,661 vials
Distribution pattern
Nationwide, Puerto Rico, Jamaica, and Grenada.

Timeline

Recall initiated
2013-11-04
FDA classified
2014-01-30
Posted by FDA
2014-02-05
Terminated
2015-03-02
Status
Terminated

Source: openFDA Drug Enforcement endpoint. Recall record D-1049-2014. The FDA issues recall classifications as health-hazard assessments, not legal findings; for legal claims consult a licensed attorney.

Class I recall: Soliris · FDA Drug Recalls