FDA Drug Recalls

Recalls / Class II

Class IID-1207-2018

Product

Minivelle (estradiol transdermal system) Patches Delivers 0.1 mg/day, a) 2 count and b) 8 count boxes, Rx only, , Mfd. by: Noven Pharmaceuticals, Inc. Miami, Florida 33186 Dist. By: Noven Therapeutics, LLC. Miami, Florida 33186 --- NDC 68968-6610-8

Brand name
Minivelle
Generic name
Estradiol
Active ingredient
Estradiol
Route
Transdermal
NDCs
68968-6610, 68968-6625, 68968-6637, 68968-6650, 68968-6675
FDA application
NDA203752
Affected lot / code info
a) 82200 Exp. 01/2019 b) 81637 Exp. 10/2018; 82200 Exp. 01/2019; 82293 Exp. 02/2019; 82600 Exp. 04/2019; 83027 Exp. 04/2019; 83173 Exp. 06/2019; 83396 Exp. 09/2019

Why it was recalled

Defective Delivery System: out of specification results for shear, an attribute related to the adhesive properties of the transdermal patches.

Recalling firm

Firm
Noven Pharmaceuticals, Inc.
Manufacturer
Noven Therapeutics, LLC
Notification channel
Letter
Type
Voluntary: Firm initiated
Address
11960 SW 144th St, Miami, Florida 33186-6109

Distribution

Quantity
213714 boxes of 8 patches and 15927 boxes of 2 patches
Distribution pattern
Nationwide

Timeline

Recall initiated
2018-09-07
FDA classified
2018-09-25
Posted by FDA
2018-10-03
Terminated
2020-09-09
Status
Terminated

Source: openFDA Drug Enforcement endpoint. Recall record D-1207-2018. The FDA issues recall classifications as health-hazard assessments, not legal findings; for legal claims consult a licensed attorney.