FDA Drug Recalls

Recalls / Class I

Class ID-1251-2014

Class I— FDA's most serious classification, issued when there is a reasonable probability that use of or exposure to the drug will cause serious adverse health consequences or death.

Product

VPRIV¿ (velaglucerase alfa for injection) , Lyophilized Powder, 400 Units/vial, Rx Only. Shire Human Genetic Therapies, Inc. 300 Shire Way, Lexington, MA 02421. NDC: 54092-701-04.

Brand name
Vpriv
Generic name
Velaglucerase Alfa
Active ingredient
Velaglucerase Alfa
Route
Intravenous
NDC
54092-701
FDA application
BLA022575
Affected lot / code info
US: Lot #: FEW13-001, FEW13-002, FED13-006; Expiry: 10/15. Mexico: Lot #: FED 013-010; Expiry: 10/15. Columbia: Lot #: FED 013-011; Expiry: 10/15.

Why it was recalled

Presence of Particulate Matter; Particulates identified as stainless steel and barium sulfate.

Recalling firm

Firm
Shire Human Genetic Therapies, Inc.
Manufacturer
Takeda Pharmaceuticals America, Inc.
Notification channel
Letter
Type
Voluntary: Firm initiated
Address
300-400 Shire Way, N/A, Lexington, Massachusetts 02421-2101

Distribution

Quantity
8359 vials
Distribution pattern
US Nationwide including Puerto Rico; Mexico, Columbia

Timeline

Recall initiated
2014-03-14
FDA classified
2014-04-18
Posted by FDA
2014-04-30
Terminated
2016-08-31
Status
Terminated

Source: openFDA Drug Enforcement endpoint. Recall record D-1251-2014. The FDA issues recall classifications as health-hazard assessments, not legal findings; for legal claims consult a licensed attorney.