FDA Drug Recalls

Recalls / Class II

Class IID-1382-2020

Product

Metformin Hydrochloride Extended-release Tablets USP 500 mg, 100 count bottles, Rx only, Manufactured for: Lupin Pharmaceuticals, Inc., Manufactured by: Lupin Limited, Goa INDIA NDC 68180-338-01

Brand name
Metformin Hydrochloride
Generic name
Metformin Hydrochloride
Active ingredient
Metformin Hydrochloride
Route
Oral
NDCs
68180-338, 68180-339
FDA application
ANDA091664
Affected lot / code info
Batch# G808201 Aug-20 G808202 Aug-20 G808200 Aug-20 G900935 Dec-20 G901311 Dec-20 G900957 Dec-20 G900958 Dec-20 G901006 Dec-20 G904803 May-21 G904804 May-21 G906551 Jul-21 G906552 Jul-21 G907375 Aug-21 G908605 Oct-21 G908604 Oct-21 G002108 Jan-22 G002109 Jan-22 G002559 Feb-22 G002560 Feb-22

Why it was recalled

CGMP Deviations: FDA analysis detected N-Nitrosodimethylamine (NDMA) impurity above the acceptable intake level

Recalling firm

Firm
Lupin Pharmaceuticals Inc.
Manufacturer
Lupin Pharmaceuticals, Inc.
Notification channel
Letter
Type
Voluntary: Firm initiated
Address
Harborplace Tower, 111 S Calvert St Fl 21st, Baltimore, Maryland 21202-6174

Distribution

Quantity
64,344 bottles
Distribution pattern
Product was distributed throughout the United States.

Timeline

Recall initiated
2020-07-07
FDA classified
2020-07-14
Posted by FDA
2020-07-22
Terminated
2021-12-23
Status
Terminated

Source: openFDA Drug Enforcement endpoint. Recall record D-1382-2020. The FDA issues recall classifications as health-hazard assessments, not legal findings; for legal claims consult a licensed attorney.

Class II recall: Metformin Hydrochloride · FDA Drug Recalls