FDA Drug Recalls

Recalls / Class II

Class IID-66318-001

Product

Prolia (denosumab) Injection, 60 mg/mL, 1 x 60 mg Single Use Prefilled Syringe per carton, Rx only, Manufactured by: Amgen Manufacturing Ltd., a subsidiary of Amgen Inc., Thousand Oaks, CA 91320-1799,NDC 55513-710-01, UPC 3 55513 71001 5.

Brand name
Prolia
Generic name
Denosumab
Active ingredient
Denosumab
Route
Subcutaneous
NDC
55513-710
FDA application
BLA125320
Affected lot / code info
Lot #: 1037592, Exp 07/15

Why it was recalled

Presence of Particulate Matter: Visible cellulose fibers were observed in a small number of prefilled syringes during a routine quality examination.

Recalling firm

Firm
Amgen, Inc.
Manufacturer
Amgen, Inc
Notification channel
Letter
Type
Voluntary: Firm initiated
Address
1 Amgen Center Dr, N/A, Thousand Oaks, California 91320-1730

Distribution

Quantity
4,163 prefilled syringes
Distribution pattern
Nationwide and Puerto Rico, Canada, Mexico, and clinical distribution in Europe.

Timeline

Recall initiated
2013-09-17
FDA classified
2013-11-04
Posted by FDA
2013-11-13
Terminated
2014-06-02
Status
Terminated

Source: openFDA Drug Enforcement endpoint. Recall record D-66318-001. The FDA issues recall classifications as health-hazard assessments, not legal findings; for legal claims consult a licensed attorney.