FDA Drug Recalls

Recalls / Class II

Class IID-820-2013

Product

AmBisome (amphotericin B) liposome for injection, 50mg vial, single use vial, For Intravenous Infusion Only, Rx Only, Marketed by: Astellas Pharma US, Inc., Northbrook, IL 60062, Manufactured by: Gilead Sciences, Inc, San Dimas, CA 91773, NDC: 0469-3051-30.

Brand name
Ambisome
Generic name
Amphotericin B
Active ingredient
Amphotericin B
Route
Intravenous
NDC
0469-3051
FDA application
NDA050740
Affected lot / code info
Lot #: 042267AA, Exp July 2015, 042287AA, 042289AA, 042291AA, Exp Aug 2015. Lot Numbers and Expiry Dates (for Canada distribution). LOT 042269AA, EXP 07/2015, LOT 0422C1AA, EXP 11/2015.

Why it was recalled

Lack of Assurance of Sterility; Astellas Pharma US, Inc. is performing a voluntary recall on certain lots of AmBisome because the manufacturer has notified Astellas that during a routine simulation of the manufacturing of AmBisome, a bacterial contamination was detected in the media fills.

Recalling firm

Firm
Astellas Pharma US Inc
Manufacturer
Astellas Pharma US, Inc.
Notification channel
Letter
Type
Voluntary: Firm initiated
Address
1 Astellas Way, N/A, Northbrook, Illinois 60062-6111

Distribution

Quantity
133,550 Vials
Distribution pattern
Nationwide and Canada

Timeline

Recall initiated
2013-06-19
FDA classified
2013-07-25
Posted by FDA
2013-07-31
Terminated
2014-02-04
Status
Terminated

Source: openFDA Drug Enforcement endpoint. Recall record D-820-2013. The FDA issues recall classifications as health-hazard assessments, not legal findings; for legal claims consult a licensed attorney.

Class II recall: Ambisome · FDA Drug Recalls